Medical disorders in pregnancy: tuberculosis: practice question

A OBG question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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OBG · Medical disorders in pregnancy: tuberculosis

Sample item

Which antitubercular drug should be avoided in pregnancy because of fetal ototoxicity?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. Streptomycin

Streptomycin crosses the placenta and causes irreversible eighth nerve damage in the fetus, so it is avoided. Isoniazid (with pyridoxine), rifampicin and ethambutol are safe, with pyrazinamide also used in India. Treatment must not be delayed.

Option by option

  • A. Streptomycin (correct)

    Correct. Aminoglycosides cause fetal ototoxicity.

  • B. Ethambutol

    Ethambutol is considered safe.

  • C. Isoniazid

    Isoniazid is safe with pyridoxine supplementation.

  • D. Rifampicin

    Rifampicin is safe in pregnancy.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More OBG questions

Questions about this OBG question

What is the answer to this OBG question?

The best answer is A, Streptomycin. Streptomycin crosses the placenta and causes irreversible eighth nerve damage in the fetus, so it is avoided.

Why is "Ethambutol" not the answer?

Ethambutol is considered safe.

Why is "Isoniazid" not the answer?

Isoniazid is safe with pyridoxine supplementation.

Why is "Rifampicin" not the answer?

Rifampicin is safe in pregnancy.

What concept does this question test?

It tests Medical disorders in pregnancy: tuberculosis in OBG. Isoniazid (with pyridoxine), rifampicin and ethambutol are safe, with pyrazinamide also used in India. Treatment must not be delayed.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Medical disorders in pregnancy: tuberculosis?

Learn management algorithms as steps: PPH, eclampsia, ectopic pregnancy. Then use the flashcards and the other OBG questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.