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General Medicine · Cardiology: hypertension in pregnancy
Sample itemA 28-year-old woman at 30 weeks of gestation has a blood pressure of 170/110 mmHg. Which antihypertensive must be avoided?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Enalapril
ACE inhibitors and angiotensin receptor blockers are contraindicated in pregnancy because they cause fetal renal dysgenesis, oligohydramnios, skull hypoplasia and neonatal renal failure. Labetalol, methyldopa and nifedipine are the usual safe agents. Magnesium sulfate is added for severe pre-eclampsia.
Option by option
A. Methyldopa
Methyldopa has a long safety record in pregnancy.
B. Labetalol
Labetalol is a standard safe choice in pregnancy.
C. Enalapril (correct)
Correct. ACE inhibitors are fetotoxic and contraindicated.
D. Nifedipine
Nifedipine is an accepted first-line agent.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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