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General Medicine · Neurology: brain abscess
Sample itemA young man with cyanotic congenital heart disease has fever, headache and a focal deficit. CT shows a 3 cm ring-enhancing lesion. Which is the appropriate management?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Stereotactic aspiration with intravenous ceftriaxone and metronidazole
Cyanotic heart disease with right-to-left shunting allows bacteria to bypass pulmonary filtration, predisposing to brain abscess, commonly with streptococci and anaerobes. Management is aspiration or drainage of lesions larger than about 2.5 cm and prolonged antibiotics covering streptococci and anaerobes. Lumbar puncture is dangerous because of raised intracranial pressure and herniation risk.
Option by option
A. Stereotactic aspiration with intravenous ceftriaxone and metronidazole (correct)
Correct. Drainage plus broad antibiotics is standard.
B. Immediate lumbar puncture
Lumbar puncture risks herniation with a mass lesion.
C. Corticosteroids alone
Steroids alone do not treat the infection.
D. Oral albendazole alone
Albendazole treats neurocysticercosis, not a pyogenic abscess.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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