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General Medicine · Neurology: viral meningitis
Sample itemA 20-year-old has fever, headache and neck stiffness. CSF shows 120 lymphocytes per microlitre, protein 70 mg/dL and glucose 60 mg/dL with a blood glucose of 90 mg/dL. What is the most likely diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Viral (aseptic) meningitis
Viral meningitis typically shows a lymphocytic pleocytosis, mildly raised protein and normal glucose. Enteroviruses are the commonest cause, and recovery is usually spontaneous. Bacterial meningitis shows neutrophils with low glucose, and tuberculous disease shows high protein with low glucose.
Option by option
A. Cryptococcal meningitis
Cryptococcal meningitis occurs in immunosuppression and shows low glucose with positive India ink or antigen.
B. Tuberculous meningitis
Tuberculous meningitis causes very high protein and low glucose.
C. Viral (aseptic) meningitis (correct)
Correct. Lymphocytes with normal glucose point to viral meningitis.
D. Pyogenic meningitis
Pyogenic meningitis causes neutrophilia and low glucose.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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