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Dermatology · Papulosquamous disorders: granuloma faciale
Sample itemA 50-year-old man has an asymptomatic, well-demarcated, brownish-red plaque on the cheek with prominent follicular openings. Biopsy shows a dense infiltrate with many eosinophils, a clear Grenz zone and leukocytoclastic vasculitis. What is the diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Granuloma faciale
Granuloma faciale is a localised leukocytoclastic vasculitis of the face with a mixed infiltrate rich in eosinophils and a Grenz zone. It is chronic, treated with topical or intralesional agents and often recurs.
Option by option
A. Discoid lupus erythematosus
Discoid lupus shows scarring, follicular plugging and an interface dermatitis.
B. Granuloma faciale (correct)
Correct. A facial plaque with eosinophils and a Grenz zone is granuloma faciale.
C. Lupus pernio
Lupus pernio is a violaceous sarcoid plaque of the nose and cheeks with non-caseating granulomas.
D. Lupus vulgaris
Lupus vulgaris shows apple-jelly nodules and tuberculoid granulomas with caseation.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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