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Radiology · Neuroimaging: chordoma
Sample itemA 55-year-old man has an expansile midline mass in the clivus with bone destruction, intratumoural calcification and very bright signal on T2 MRI. What is the likely tumour?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Chordoma
Chordomas arise from notochordal remnants along the clivus or sacrum, destroy bone and show markedly high T2 signal with a honeycomb enhancement pattern. They are locally aggressive and recur.
Option by option
A. Craniopharyngioma
A craniopharyngioma is suprasellar with cysts and calcification.
B. Pituitary adenoma
A pituitary adenoma sits in the sella and does not destroy the clivus in this way.
C. Meningioma
A meningioma shows hyperostosis and a dural tail.
D. Chordoma (correct)
Correct. A destructive midline clival mass with bright T2 signal is a chordoma.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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