Immunopathology: practice question

A Pathology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pathology · Immunopathology

Sample item

What is the pathologic hallmark of rheumatoid arthritis?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. Chronic synovitis with pannus

Rheumatoid arthritis causes persistent autoimmune synovitis that forms pannus, which erodes cartilage and bone and leads to progressive joint damage.

Option by option

  • A. Chronic synovitis with pannus (correct)

    Correct: pannus from chronic synovitis erodes joints in rheumatoid arthritis.

  • B. Amyloid only

    Amyloid is not the defining joint lesion.

  • C. Acute neutrophilic abscess

    Acute abscess is a suppurative infection pattern.

  • D. Caseous necrosis

    Caseous necrosis is classically associated with tuberculosis.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Pathology questions

Questions about this Pathology question

What is the answer to this Pathology question?

The best answer is A, Chronic synovitis with pannus. Rheumatoid arthritis causes persistent autoimmune synovitis that forms pannus, which erodes cartilage and bone and leads to progressive joint damage.

Why is "Amyloid only" not the answer?

Amyloid is not the defining joint lesion.

Why is "Acute neutrophilic abscess" not the answer?

Acute abscess is a suppurative infection pattern.

Why is "Caseous necrosis" not the answer?

Caseous necrosis is classically associated with tuberculosis.

What concept does this question test?

It tests Immunopathology in Pathology. The correct option holds because: Correct: pannus from chronic synovitis erodes joints in rheumatoid arthritis.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Immunopathology?

Learn each disease as a bundle: cause, key histology, markers, and the clinical hallmark. Then use the flashcards and the other Pathology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.