Autoimmune disease: rheumatoid arthritis: practice question

A Pathology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pathology · Autoimmune disease: rheumatoid arthritis

Sample item

What destructive tissue forms over articular cartilage in rheumatoid arthritis?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. Pannus

Rheumatoid arthritis produces proliferative inflamed synovium called pannus, which erodes cartilage, bone, and tendons. Chronic immune activation drives joint destruction and deformity.

Option by option

  • A. Tophus

    Tophi are deposits of monosodium urate in gout.

  • B. Granulation tissue only in skin

    Skin granulation tissue is part of wound repair, not the joint lesion.

  • C. Pannus (correct)

    Correct. Pannus is invasive synovial tissue in rheumatoid joints.

  • D. Amyloid plaque

    Amyloid plaques are unrelated to RA cartilage erosion.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Pathology questions

Questions about this Pathology question

What is the answer to this Pathology question?

The best answer is C, Pannus. Rheumatoid arthritis produces proliferative inflamed synovium called pannus, which erodes cartilage, bone, and tendons.

Why is "Tophus" not the answer?

Tophi are deposits of monosodium urate in gout.

Why is "Granulation tissue only in skin" not the answer?

Skin granulation tissue is part of wound repair, not the joint lesion.

Why is "Amyloid plaque" not the answer?

Amyloid plaques are unrelated to RA cartilage erosion.

What concept does this question test?

It tests Autoimmune disease: rheumatoid arthritis in Pathology. Chronic immune activation drives joint destruction and deformity.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Autoimmune disease: rheumatoid arthritis?

Learn each disease as a bundle: cause, key histology, markers, and the clinical hallmark. Then use the flashcards and the other Pathology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.